I finally got to sweeping the front porch and patio, weeding between the bricks and pulling weeds here and there in the front garden. I also started to work down the bricks along the laneway. It will take a bit of time to get that all done but then it will look lovely for a few days until the weeds grow again - hardy little things! A large bag of weeds and big branches that came down in the wind went out to the street for Collection Day. I just happened to walk to the back of the yard and discovered these large branches from the maple tree on the ground so that too is all cleared away. My daughter weeded the sunflowers although left enough weed that hopefully the rabbit will eat that instead of the sunflowers which are getting tougher stems and leaves now so less appealing. Next year, if we are still here, we will fence it at the beginning so that all the seeds get to grow. It was meant to be a large block of sunflowers.
Some weeding in the back yard but not a great deal. The one side looks much as Edward last set it up but the other side, deteriorated greatly from last year, and putting in the new fences did not particularly help that. But as I approach 80 I am satisfied that I am at least keeping the grass cut with my daughter's help. I am not a gardener at the best of times but rather I just helped Edward through the 54.5 years of our marriage. All of us would have liked to have had him survive but life doesn't always flow the way we would like.
Completed Chromosome 1 and there are a few very minor changes in the cross over points - a couple of them were very close together and the new results from Living DNA shows that these are shared crossover points for two siblings which makes it much neater. Two cross over points are somewhat ambiguous but the rest are within a couple of numbers of the original numbers obtained using 23 and Me data along with Gedmatch. I continue with just two crossover points on this longest chromosome. I did discover that the Fred Hutchinson Cancer Center states that it is typical to have 2-3 crossover points per chromosome during meiosis. It does look like 2 to 3 is the average for Homo sapiens on individual chromosomes. DNAeXplained mentions that Chromosome 1 has three crossovers 27% of the time. So that was interesting as well. With five sibling results I found that to be between 2 and 5 crossovers on Chromosome 1. In total for five siblings 40 chromosomes out of a total of 5x2x22 chromosomes were inherited without a crossover which will be verified by this work. That is 18% of the chromosomes inherited from our parents were passed unchanged from their parents. DNAeXplained mentions that 94% of offspring will inherit between 4 and 12 chromosomes that have no crossover points (i.e. inherited from a single grandparent). The 40 is an average between these two numbers 4 and 12 but slightly on the low side so that is also very interesting. Homo sapiens is refreshed each generation by the exchange of genes and it would appear that on average most meiotic events occur in an average exchange of chromosomal material at conception.
We have much to learn about DNA and in general the best process is the natural process. However if people are willing to pay for it correction can be made for mitochondrial disease and eliminating harmful sections of DNA in order to produce a viable offspring. Do I believe in this? coming out of science background I cannot deny that benefits are perhaps available to people but we need a generation of testing to ensure that we do not upset the natural process which is always the best. What happens naturally in nature is generally the most forward way to move. Lifestyle has far more to do with a successful life than anything else but there are diseases that can curtail life for those unfortunate babies born with mitochondrial disease or other non-life supporting disabilities. But one must remember that Einstein did not speak until he was ten years of age - he had nothing to say that he valued up to that point presumably. So one must be careful how one judges the forward movement of children in learning. That is why AI is useless as a teacher but can be utilized under the control of researchers in a systematic manner to enable a much further reach into the literature in a much shorter period of time. But skill and craftsmanship will always be better than AI which is really only a computer that we set up to serve a purpose.
Today will be more work on the laneway perhaps; time will tell. Definitely I have plans to work on my matches and get them into the databases (chromosome 1 was just a feeler as to what might be there in this new data). Yesterday was weight lifting as the extra exercise so today is rowing for sure and whatever else comes to mind as the day flows forward.
Drinking my tea having put away the items in the dishwasher and the first set of yoga-stretching exercises are completed. The next set just before breakfast again primarily walking and yoga along with one set of 100 jumping jacks. The day continues and I must get on with it. Solitaire puzzles are next for a bit of a brain teaser.
One of these new style light fixtures wore out and we have four of them that are wired in (Edward loved all the new things for sure!). That is not really practical so will replace with screw in type fixtures over the next little bit. I need to go to the store and pick something out and find someone to do the work. I could do it but will do the right thing and employ someone locally if I can find someone. The washing machine will hopefully be repaired on Tuesday and today is Saturday and looks to be a lovely day. We had a good time kayaking and walking yesterday after working in the garden.
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