I finally got all of my ancestry accounts up to date with DNA matches. A couple of new and interesting ones that continue to point to my Buller line and likely the X chromosome. I do not know these people at all but do know their ancestry from their trees. There is one portion of the X chromosome that has come directly to all of us from Sarah (Cheatle) Welch who was my 3x great grandmother. Her daughter Ann (Welch) Buller) married Henry Christopher Buller and they had eleven children Ann's X chromosome was passed to my maternal grandmother intact from her father hence the strong matches on the X chromosome. Interesting that such a good length passed from a 3x great grandmother to us. But only some of us of my seven siblings only five have tested and only three have inherited this rather interesting length which varies between 18 cM and 28 cM with most around 25 cM. Occasionally one of the Ancestry customers posts their DNA to Gedmatch but I also have matches at 23 and Me and FT DNA just to give me a rather well rounded look at the DNA and its ancestry back to Sarah Cheatle. Sarah's mother is also named Sarah and may be Sarah Bonnell who married a William Cheatle 7 Jan 1752 at All Saints Loughborough, Leicestershire.
Showing posts with label X Chromosome. Show all posts
Showing posts with label X Chromosome. Show all posts
Saturday, August 14, 2021
Ancestry matches
Monday, December 31, 2018
Chromosome 23
Still I am perplexed by Chromosome 23 and how to divide up the maternal portion I inherited from my mother. I have two known matches by 4th cousins but the length is really insufficient to say positively that I have phased this Chromosome 23 correctly between my two maternal grandparents lines - Pincombe and Buller. I have one match on my Routledge line (my great grandmother Grace Gray married William Robert Pincombe and this match descends from a sister of Grace's mother Elizabeth Mary Ann Routledge). I have one match on my Welch line and in this case the descent is from the twin sister of my 2x great grandmother Anne Welch who married Henry Christopher Buller. The amount shared is 10cM for the Routledge match and 8 cM for the Welch match. Fortunately they do not fall in the same area but they confuse a phased X chromosome which I produced prior to knowledge of these two matches. Do I go with the matches or do I go with the carefully thought through phasing that I did before the matches appeared? I am ambivalent. I wish I could find one of my known 2nd cousin Buller as their grandmother was my grandmother's sister. Likely we will share some X chromosome enough to convince me one way or another on how we have inherited our X chromosome from our mother. The paternal X chromosome is, of course, easy as that is inherited entirely from my father who received it unchanged from his mother and it was inherited by her from her parents - William Rawlins and Elizabeth (Lywood) Rawlins.
I have a new match on Ancestry lately which is also descendant of my Buller side likely back to my 2x great grandmother Anne Welch. It would be interesting to see if this individual has an X chromosome match with me. However, I have not yet written but will contemplate doing that to see if it interests him to pursue the match. It is a large match. Another similar match at 23 and Me is likely Welch-Buller with a 1.2% match and in this case the chromosomes have not been shared. I did write to this individual and verified our descent from the Welch family as being our most recent common ancestor. Perhaps over time she may share her chromosome results and again a strong possibility that there would be X chromosome results of a length sufficient to name the phased portions of the X chromosome with more accuracy.
I have a new match on Ancestry lately which is also descendant of my Buller side likely back to my 2x great grandmother Anne Welch. It would be interesting to see if this individual has an X chromosome match with me. However, I have not yet written but will contemplate doing that to see if it interests him to pursue the match. It is a large match. Another similar match at 23 and Me is likely Welch-Buller with a 1.2% match and in this case the chromosomes have not been shared. I did write to this individual and verified our descent from the Welch family as being our most recent common ancestor. Perhaps over time she may share her chromosome results and again a strong possibility that there would be X chromosome results of a length sufficient to name the phased portions of the X chromosome with more accuracy.
Sunday, July 26, 2015
DNA and Surname Studies
I gave a Google Hangout on Saturday for The Surname Society on DNA and Surname Studies and promised to share it with my blog. I belong to both The Guild of One-Name Studies and The Surname Society. My world wide one-name studies are at the Guild and my localized one name studies are at The Surname Society.
http://www.kipp-blake-families.ca/TSS-Hangout-25Jul2015-DNA%20and%20Surname%20Studies.pptx
Slide 1
Title Page (PLCGS is an acronym for Professional Learning Certificate in Genealogical Studies which I obtained from The National Institute for Genealogical Studies which was based at the University of Toronto in the Faculty of Information Studies when I graduated in 2007 in English and Canadian Studies).
Slide 2
List of Useful books for DNA and Surname Studies
Slide 3
I find this useful to add as I want people to realize what they may learn from DNA testing and how one should approach this rather novel and progressive way of looking at your genealogy. Personally it was the advent of DNA testing (and my cousin's prompting as he wanted a profile of my emigrant Pincombe family for a local history book) that really brought me into genealogy as I felt that I could actually prove my ancestry.
Slide 4
Useful abbreviations
Slide 5
I like all the testing companies that I have used. I do not have any actual preference as they have all served the purpose that I had in mind when I tested at them.
Slide 6
Getting into the nitty-gritty now, I suggest that if anyone wants to join a project that you manage you should let them unless they really do not carry the surname that you are looking for at all or do not belong to the particular haplogroup of which you are administrator/co-administrator.
Slide 7
My summary of the talk to follow. The first six slides were a warmup to get into the topic itself. From this point the slides assume some knowledge of the different types of DNA although I do give a brief overlook.
Slide 8
List of the DNA that I am going to look at and for the moment is the DNA tested by the companies at which I have tested either myself or my brother.
Slide 9
Y DNA or the Male line in one's ancestry. Our father may be known (as in my case) or unknown to us but the Y DNA which the sons of any particular male carry traces his line back generation upon generation to the first individual who carried that exact genetic signature (although a few mutations could have crept in through the centuries).
Slide 10
Autosomal DNA which is contributed to by all our ancestors although they may not all show up in the resultant set that we receive because that is the luck of the draw one might say. I believe that autosomal DNA is now coming into its own and is quite important in DNA projects.
Slide 11
X chromosome is the mate to the Y chromosome in males and females receive an X chromosome from each parent. In males there are a limited number of people who will match you because your X chromosome is solely from your mother so is entirely her side of the family and excludes her father's father's line. but does include her father's mother's line since that is the exact chromosome which he has passed to his daughters. Perhaps not useful for Surname Studies but could prove interesting on occasion when sorting through matches.
Slide 12
Mitochondrial DNA probably has very little use in Surname Studies but I do mention one and that is geographic location for emigrant ancestors. Really not pertinent if you already know where your ancestors lived but in the case of people whose ancestors emigrated in the 1600s (or long before that actually when one looks at the First Peoples to the Western Hemisphere) as a married couple the mitochondrial DNA might point to a location where the particular haplogroup subclade is found.
Slide 13
Case Studies to be examined include my husband's Kipp/Kip one name study and two of my one name studies Pincombe and Blake.
Slide 14
My husband has been running his KIPP/KIP study at FT DNA for over six years now. His purpose was to find the genetic signature for this rather interesting family. His own line goes back to his 2x great grandfather Isaac KIPP who was born in 1764 likely at Northeast Town in Dutchess County where he is found on the census with his wife Hannah in 1790 living next to or with his father in law Jonathan Mead. Was this KIPP family the New Amsterdam family from the late 1630s (emigrated from Amsterdam Holland) or was it one of the KIPP families that was naturalized in the 1750s coming from the Germanic States. These two groups are the ancestors of many of the KIPP/KIP families in North America.
Slide 15
I then discussed the KIPP study and the members and that the study determined that this was not a singleton surname by the Y DNA results.
Slide 16
A list of the first 12 markers found for the New Amsterdam family and the significance of DYS426 being 13 in this family grouping thus separating this KIPP/KIP family from the other KIPP families in North America. There are differences in CDYa/b which it is hoped will permit separation of the three sons of the original emigrant or perhaps sons of those sons. That is still being worked on as this part of the study slowly grows.
Slide 17
I summarized the comments above noting that one of the other study groups has similar results in the first 12 markers except for the significant DYS426 which is 12 in that family but they also have other differences which results in a Genetic Distance of 6 or 7 on 37 markers. Hence they are not the same family in a genealogical timeframe. My husband has done a lot of research on Dutch records now and has determined that at least prior to 1600 (and not sure how far back before that time) this family lived in the border area of Denmark/Netherlands/Germany although in the territory known as The Netherlands at that time.
Slide 18
One of my pet recommendations to anyone in a surname group that I am involved with is to encourage them to join the relevant haplogroup project for their surname. The administrators of the Haplogroup projects have been very aggressive in putting together fantastic phylogenetic charts of their members and I include an image that I wasn't able to show yesterday due to technical problems at my end.
This particular chart is for my Blake line (Blayke) and note that CTS4122+ separates my Blayke from Blake beside it. The interesting part of all of this is that my grandfather worked with the ancestor of this tester in the Train Yards at Eastleigh and they wondered if they were related. Probably not in a thousand years one might suspect. But interesting to see how the administrators are putting together their information into charts into a genealogical timeframe.
Slide 19
A second case study and this one for my PINCOMBE/PINKHAM one name study. This slide talks about some of the people who have tested and how these results looked. As a result of the first two items I decided to set the Y DNA study aside for several years. The third bullet item brought it back to life again and the fourth bullet item provides a short historical reference to a will that I have transcribed and how it might work into the story of bullet three.
Slide 20
This is my PINCOMBE family tree from my grandfather back to his furtherest back known ancestor (lived at North Molton, Devon). The black arrow marks the most recent common ancestor for the PINCOMBE tester in Australia and myself. John PINCOMBE (b 1808 Bishops Nympton, Devon) is my emigrant ancestor.
Slide 21
I talked about the problems that I had with this PINCOMBE/PINKHAM single surname study. Mostly it is the small group of testers and no matches. My history of this family is known back to about 1485 but the other testers are looking at the latter part of the 1600s for their furtherest back ancestor. I found some interesting earlier history for the PENCOMBE (spelling used by the earliest PINCOMBE at North Molton, Devon) family in Herefordshire in the 1300s. At the time of the mismatch I also noted that the surname PINKHAM was found in Devon/Cornwall earlier than 1485.
Slide 22
My PINCOMBE/PINKHAM study was an inherited one from an earlier researcher to whom I am not
related as far as I know. The earlier study had been deposited at the Society of Genealogists, London, England, UK and the original researcher Dr Richard PINKHAM (Gloucestershire) had begun this study prior to WWII when he first collected his information including abstracting the wills at the Devon Record Office (bombed in WWII and all records destroyed). I do not want to undo 50+ years of research; I do not mind incorporating new material into the existing study. So I adopted a wait and see attitude as my method of resolving the conflict mentioned in Slide 19.
Slide 23
Resolving such a difficulty may not occur very quickly and there are several other ways to look at a study anyway so I continued (and still continue) collecting documental evidence for the PINCOMBE/PINKHAM family. I blog about the Pincombe family and with my own success with Family Finder and PINCOMBE/PINKHAM really encourage any female PINCOMBE/PINKHAM to test with Family Finder and join the project. Then luck enters into the equation and the match in Sweden is certainly very very interesting especially as his haplogroup is not very common in Sweden (more common in the British Isles).
Slide 24
Autosomal DNA has played a role in the PINCOMBE/PINKHAM study as I have two different matches one with a known fourth cousin and one with a known third cousin once removed with our common ancestor being in the PINCOMBE family. I mention that finding a descendant of the John PINCOMBE and Johane BLACKMOORE family would add greatly to the study and prove this line although the paper proof is probably more than adequate (I have transcribed the entire set of parish registers at Bishops Nympton) the DNA verification is always exciting as well.
Slide 25
The BLAKE/BLEAK study is the final case study in this presentation looking at Y DNA principally with a little autosomal mentioned. The actual Y DNA study is administered by Bill BLEAK although I am a co-administrator along with two others. This study although begun in 2004 is still in its infancy. Interesting results are coming out of it but more testers are needed. With such a large surname 50+ testers is not enough to really draw a lot of conclusions. I publish the Blake Newsletter four times a year and report on the DNA progress of the study there.
Slide 26
A little background on the Blake one name study.
Slide 27
This Case Study looks at the descendants of a group of families - PARLEE/ALLEN/FOLKINS and I mention GedMatch as being a good site to enter your results and collect your matches by surname if possible or at least by matches.
Slide 28
More on the PARLEE/ALLEN/FOLKINS families and they descend from United Empire Loyalists brought to New Brunswick by the British following the American Revolution. I propose that as you put known cousins into the Chromosome Browser start marking portions of the Chromosome as belonging to a particular surname if possible. As you acquire more and more members it may be possible to find particular areas that are specific to a surname and then when unknown but likely related people join you can predict their lineage by their matches. An interesting way to look at surname projects I think.
Slide 29
Talked about mitochondrial DNA project and I am involved in two - the T haplogroup project and the H11 project. both at FT DNA.
Slide 30
H11 Haplogroup phylogenetic chart (build of February 2014). I have over 100 members in my study with their full genetic scan and a couple of these subclades appear to belong to particular areas in Europe (Europe includes both East and West). My own haplogroup H11a2a1 appears to be NorthWestern Europe and primarily the British Isles). The haplogroup H11a2a2 is primarily an Eastern European group. H11b1 appears to be mostly Eastern Europe extending into Central Europe.
Slide 31
Mitochondrial DNA is not really useful in Surname studies except perhaps that a location of an emigrant couple might be discovered.
Slide 32
X chromosome studies is again the least useful in Surname Studies. Males have limited matches so might prove useful on occasion.
Slide 33
Quick review of the benefits and drawbacks to Y DNA studies although I think that testing your paternal line is absolutely essential and any drawbacks are really very unimportant. How to attract members is always a problem but publicizing your study is the best means.
Slide 34
A query slide with my email but I should mention my knowledge of DNA is limited to the above.
Slide 35
List of suggested books and I do own them all and find each of them to be most useful.
Slide 36
Thank you for reading this far!
http://www.kipp-blake-families.ca/TSS-Hangout-25Jul2015-DNA%20and%20Surname%20Studies.pptx
Slide 1
Title Page (PLCGS is an acronym for Professional Learning Certificate in Genealogical Studies which I obtained from The National Institute for Genealogical Studies which was based at the University of Toronto in the Faculty of Information Studies when I graduated in 2007 in English and Canadian Studies).
Slide 2
List of Useful books for DNA and Surname Studies
Slide 3
I find this useful to add as I want people to realize what they may learn from DNA testing and how one should approach this rather novel and progressive way of looking at your genealogy. Personally it was the advent of DNA testing (and my cousin's prompting as he wanted a profile of my emigrant Pincombe family for a local history book) that really brought me into genealogy as I felt that I could actually prove my ancestry.
Slide 4
Useful abbreviations
Slide 5
I like all the testing companies that I have used. I do not have any actual preference as they have all served the purpose that I had in mind when I tested at them.
Slide 6
Getting into the nitty-gritty now, I suggest that if anyone wants to join a project that you manage you should let them unless they really do not carry the surname that you are looking for at all or do not belong to the particular haplogroup of which you are administrator/co-administrator.
Slide 7
My summary of the talk to follow. The first six slides were a warmup to get into the topic itself. From this point the slides assume some knowledge of the different types of DNA although I do give a brief overlook.
Slide 8
List of the DNA that I am going to look at and for the moment is the DNA tested by the companies at which I have tested either myself or my brother.
Slide 9
Y DNA or the Male line in one's ancestry. Our father may be known (as in my case) or unknown to us but the Y DNA which the sons of any particular male carry traces his line back generation upon generation to the first individual who carried that exact genetic signature (although a few mutations could have crept in through the centuries).
Slide 10
Autosomal DNA which is contributed to by all our ancestors although they may not all show up in the resultant set that we receive because that is the luck of the draw one might say. I believe that autosomal DNA is now coming into its own and is quite important in DNA projects.
Slide 11
X chromosome is the mate to the Y chromosome in males and females receive an X chromosome from each parent. In males there are a limited number of people who will match you because your X chromosome is solely from your mother so is entirely her side of the family and excludes her father's father's line. but does include her father's mother's line since that is the exact chromosome which he has passed to his daughters. Perhaps not useful for Surname Studies but could prove interesting on occasion when sorting through matches.
Slide 12
Mitochondrial DNA probably has very little use in Surname Studies but I do mention one and that is geographic location for emigrant ancestors. Really not pertinent if you already know where your ancestors lived but in the case of people whose ancestors emigrated in the 1600s (or long before that actually when one looks at the First Peoples to the Western Hemisphere) as a married couple the mitochondrial DNA might point to a location where the particular haplogroup subclade is found.
Slide 13
Case Studies to be examined include my husband's Kipp/Kip one name study and two of my one name studies Pincombe and Blake.
Slide 14
My husband has been running his KIPP/KIP study at FT DNA for over six years now. His purpose was to find the genetic signature for this rather interesting family. His own line goes back to his 2x great grandfather Isaac KIPP who was born in 1764 likely at Northeast Town in Dutchess County where he is found on the census with his wife Hannah in 1790 living next to or with his father in law Jonathan Mead. Was this KIPP family the New Amsterdam family from the late 1630s (emigrated from Amsterdam Holland) or was it one of the KIPP families that was naturalized in the 1750s coming from the Germanic States. These two groups are the ancestors of many of the KIPP/KIP families in North America.
Slide 15
I then discussed the KIPP study and the members and that the study determined that this was not a singleton surname by the Y DNA results.
Slide 16
A list of the first 12 markers found for the New Amsterdam family and the significance of DYS426 being 13 in this family grouping thus separating this KIPP/KIP family from the other KIPP families in North America. There are differences in CDYa/b which it is hoped will permit separation of the three sons of the original emigrant or perhaps sons of those sons. That is still being worked on as this part of the study slowly grows.
Slide 17
I summarized the comments above noting that one of the other study groups has similar results in the first 12 markers except for the significant DYS426 which is 12 in that family but they also have other differences which results in a Genetic Distance of 6 or 7 on 37 markers. Hence they are not the same family in a genealogical timeframe. My husband has done a lot of research on Dutch records now and has determined that at least prior to 1600 (and not sure how far back before that time) this family lived in the border area of Denmark/Netherlands/Germany although in the territory known as The Netherlands at that time.
Slide 18
One of my pet recommendations to anyone in a surname group that I am involved with is to encourage them to join the relevant haplogroup project for their surname. The administrators of the Haplogroup projects have been very aggressive in putting together fantastic phylogenetic charts of their members and I include an image that I wasn't able to show yesterday due to technical problems at my end.
This particular chart is for my Blake line (Blayke) and note that CTS4122+ separates my Blayke from Blake beside it. The interesting part of all of this is that my grandfather worked with the ancestor of this tester in the Train Yards at Eastleigh and they wondered if they were related. Probably not in a thousand years one might suspect. But interesting to see how the administrators are putting together their information into charts into a genealogical timeframe.
Slide 19
A second case study and this one for my PINCOMBE/PINKHAM one name study. This slide talks about some of the people who have tested and how these results looked. As a result of the first two items I decided to set the Y DNA study aside for several years. The third bullet item brought it back to life again and the fourth bullet item provides a short historical reference to a will that I have transcribed and how it might work into the story of bullet three.
Slide 20
This is my PINCOMBE family tree from my grandfather back to his furtherest back known ancestor (lived at North Molton, Devon). The black arrow marks the most recent common ancestor for the PINCOMBE tester in Australia and myself. John PINCOMBE (b 1808 Bishops Nympton, Devon) is my emigrant ancestor.
Slide 21
I talked about the problems that I had with this PINCOMBE/PINKHAM single surname study. Mostly it is the small group of testers and no matches. My history of this family is known back to about 1485 but the other testers are looking at the latter part of the 1600s for their furtherest back ancestor. I found some interesting earlier history for the PENCOMBE (spelling used by the earliest PINCOMBE at North Molton, Devon) family in Herefordshire in the 1300s. At the time of the mismatch I also noted that the surname PINKHAM was found in Devon/Cornwall earlier than 1485.
Slide 22
My PINCOMBE/PINKHAM study was an inherited one from an earlier researcher to whom I am not
related as far as I know. The earlier study had been deposited at the Society of Genealogists, London, England, UK and the original researcher Dr Richard PINKHAM (Gloucestershire) had begun this study prior to WWII when he first collected his information including abstracting the wills at the Devon Record Office (bombed in WWII and all records destroyed). I do not want to undo 50+ years of research; I do not mind incorporating new material into the existing study. So I adopted a wait and see attitude as my method of resolving the conflict mentioned in Slide 19.
Slide 23
Resolving such a difficulty may not occur very quickly and there are several other ways to look at a study anyway so I continued (and still continue) collecting documental evidence for the PINCOMBE/PINKHAM family. I blog about the Pincombe family and with my own success with Family Finder and PINCOMBE/PINKHAM really encourage any female PINCOMBE/PINKHAM to test with Family Finder and join the project. Then luck enters into the equation and the match in Sweden is certainly very very interesting especially as his haplogroup is not very common in Sweden (more common in the British Isles).
Slide 24
Autosomal DNA has played a role in the PINCOMBE/PINKHAM study as I have two different matches one with a known fourth cousin and one with a known third cousin once removed with our common ancestor being in the PINCOMBE family. I mention that finding a descendant of the John PINCOMBE and Johane BLACKMOORE family would add greatly to the study and prove this line although the paper proof is probably more than adequate (I have transcribed the entire set of parish registers at Bishops Nympton) the DNA verification is always exciting as well.
Slide 25
The BLAKE/BLEAK study is the final case study in this presentation looking at Y DNA principally with a little autosomal mentioned. The actual Y DNA study is administered by Bill BLEAK although I am a co-administrator along with two others. This study although begun in 2004 is still in its infancy. Interesting results are coming out of it but more testers are needed. With such a large surname 50+ testers is not enough to really draw a lot of conclusions. I publish the Blake Newsletter four times a year and report on the DNA progress of the study there.
Slide 26
A little background on the Blake one name study.
Slide 27
This Case Study looks at the descendants of a group of families - PARLEE/ALLEN/FOLKINS and I mention GedMatch as being a good site to enter your results and collect your matches by surname if possible or at least by matches.
Slide 28
More on the PARLEE/ALLEN/FOLKINS families and they descend from United Empire Loyalists brought to New Brunswick by the British following the American Revolution. I propose that as you put known cousins into the Chromosome Browser start marking portions of the Chromosome as belonging to a particular surname if possible. As you acquire more and more members it may be possible to find particular areas that are specific to a surname and then when unknown but likely related people join you can predict their lineage by their matches. An interesting way to look at surname projects I think.
Slide 29
Talked about mitochondrial DNA project and I am involved in two - the T haplogroup project and the H11 project. both at FT DNA.
Slide 30
H11 Haplogroup phylogenetic chart (build of February 2014). I have over 100 members in my study with their full genetic scan and a couple of these subclades appear to belong to particular areas in Europe (Europe includes both East and West). My own haplogroup H11a2a1 appears to be NorthWestern Europe and primarily the British Isles). The haplogroup H11a2a2 is primarily an Eastern European group. H11b1 appears to be mostly Eastern Europe extending into Central Europe.
Slide 31
Mitochondrial DNA is not really useful in Surname studies except perhaps that a location of an emigrant couple might be discovered.
Slide 32
X chromosome studies is again the least useful in Surname Studies. Males have limited matches so might prove useful on occasion.
Slide 33
Quick review of the benefits and drawbacks to Y DNA studies although I think that testing your paternal line is absolutely essential and any drawbacks are really very unimportant. How to attract members is always a problem but publicizing your study is the best means.
Slide 34
A query slide with my email but I should mention my knowledge of DNA is limited to the above.
Slide 35
List of suggested books and I do own them all and find each of them to be most useful.
Slide 36
Thank you for reading this far!
Tuesday, June 30, 2015
Phasing the X chromosome for parents from yourself and siblings
I decided to look at the X chromosomes of my parents and for my brother of course as that is his only X chromosome and from our mother. My father has only one X chromosome and my brother's results do not show any information presumably for my father's X chromosome since only a Y is passed to a male child with my sister and I receiving an X chromosome from our father which he received from his mother and therein lies the mystery. Why do my sister and I not have the exact same results since the X does not recombine? I had to think this one through. My brother's result is the X chromosome that results from the recombination of our mother's two X chromosomes hence he has no effect on how we look at our father's X chromosome.
As I work my way down there are occasional spots where the X chromosome which my brother received does not allow for the result that my sister and I have received so at that point it becomes either TT or CT / CC or AC / GG or AG etc. So what does this actually mean and does it then become useful to phase the X chromosome. When one looks at the chromosome browser one would think that the three of us matched exactly but a half/match gives the same result as a full/match. If there are two results for some snps on the helix then presumably one of them is switched off so that it is not expressed. I think I am beginning to understand x transmission and why males suffer more from x transmitted diseases because they do not have a second x chromosome to switch off particular snps that are recessive and perhaps unhealthy. I must admit to finding all of this very intriguing. I had a great deal of interest in DNA when I attended University in the 60s but it was still a new field and not yet down into undergraduate courses in a way that I would have found it more fascinating that Honours Chemistry which I did study. For the most part what we received, my sister, and I follows through quite logically although looking through as I now am I can see that in the first 50 snps there are seven either/or in my mother's results or 14% difference between the X chromosome which we inherited and the one that my brother inherited and we roughly share that difference 50/50.
The Xchromosome is also interesting because it lets us look at particular matches that we may have.
I have nine pages of X matches (90) at FT DNA my sister has 13 pages (130) and my brother has only 3 matches which includes his two sisters and one individual that I can not place. The match has a fairly extensive tree and I can find a couple of lines that might be interesting but the X chromosome is our mother's lines and the Dorset that comes up is on our Father's side. My brother does not share this match with us and it actually includes two sets of surnames and two single surnames with just one that has a tree (but just because they match this singleton match does not mean that they match my brother necessarily). This is actually his first match outside the family so is rather interesting. The tree shows a family with deep Virginia/North Carolina roots and then moving west from there as far as Texas. He is said to be a 4th-distant cousin. To look at X matches for a male the restriction is always towards the female, so our mother and her paternal grandmother and her mother/maternal grandparents but excluding the male line further back each time so always following the female portion plus the husband of the female at each level. That means I am looking at Grace Gray whose family lines were from Bewcastle, Cumberland and Etton/Holme on the Wolds East Riding of Yorkshire; I am looking at Ellen Rosina Buller whose father was born in Birmingham and his mother born at Lichfield with the father from Rugeley Staffordshire and the mother from Ashby de la Zouch Leicestershire and Ellen's mother who is my mystery lady born at Birmingham of parents possibly Thomas Taylor and Ellen Roberts whose lineage both stretches back one more generation at Birmingham and then unknown for Taylor and Warwickshire/Shropshire for the Roberts lines moving back. So a fifth cousin I am looking at 4x great grandparents and comparing that with a chart of ancestry that dates back into early colonial Virginia without any known debarkation point for the emigrant ancestor is virtually impossible. But it is interesting none the less to see that there is only one individual who matches my brother other than his sisters on the X chromosome. That tells me that not very many have tested in these lines but the potential is now there for them to do so as Ancestry moves into the British Isles.
One of my strongest X matches (3rd to 5th cousin with 60.32 cM shared) other than my siblings is with someone whose father's paternal grandmother came directly from Ireland born circa 1850. Anna Foster born 1850 Ireland and the daughter of Robert Foster. She is rather interesting because Anna would have received from her father Robert his only X chromosome passed directly to him from his mother and unaltered in this exchange. Anna then would have passed to her daughter in this case this X chromosome from her father and the one she received from her mother and the two would recombine to form a new X chromosome along with the X chromosome which she received from her father who again received it as passed from his mother whose family tree goes back into Yorkshire and Ireland (an interesting combination). Her mother's side is principally from Ohio/Missouri and before that Virginia. American ancestry is quite fascinating with the variety of ancestral locations to be found in their lines. Comparing her to other known lines she shares almost the same on the X chromosome as another match said to be 2nd to 4th cousin. On Chromosome 11 I have three people with known Irish ancestry who share DNA at almost the same location. Makes you wonder if this is a special block inherited by a number of Irish families. But the largest parts that I share with each of these four individuals including the one I am discussing are on different chromosomes. I need to have more people test that are known to me but that is really difficult given that we have no first cousins, few second cousins and half second cousins but many many third cousins that I do not personally know.
I shall continue working on the phasing of the X chromosomes with somewhat more knowledge than before I think. Discussion even with oneself can be quite beneficial if properly channelled! My living memory has been most beneficial to me and on occasion from comments received has proven to be handy to others which was a side product that I never anticipated when I started my blog in 2008.
As I work my way down there are occasional spots where the X chromosome which my brother received does not allow for the result that my sister and I have received so at that point it becomes either TT or CT / CC or AC / GG or AG etc. So what does this actually mean and does it then become useful to phase the X chromosome. When one looks at the chromosome browser one would think that the three of us matched exactly but a half/match gives the same result as a full/match. If there are two results for some snps on the helix then presumably one of them is switched off so that it is not expressed. I think I am beginning to understand x transmission and why males suffer more from x transmitted diseases because they do not have a second x chromosome to switch off particular snps that are recessive and perhaps unhealthy. I must admit to finding all of this very intriguing. I had a great deal of interest in DNA when I attended University in the 60s but it was still a new field and not yet down into undergraduate courses in a way that I would have found it more fascinating that Honours Chemistry which I did study. For the most part what we received, my sister, and I follows through quite logically although looking through as I now am I can see that in the first 50 snps there are seven either/or in my mother's results or 14% difference between the X chromosome which we inherited and the one that my brother inherited and we roughly share that difference 50/50.
The Xchromosome is also interesting because it lets us look at particular matches that we may have.
I have nine pages of X matches (90) at FT DNA my sister has 13 pages (130) and my brother has only 3 matches which includes his two sisters and one individual that I can not place. The match has a fairly extensive tree and I can find a couple of lines that might be interesting but the X chromosome is our mother's lines and the Dorset that comes up is on our Father's side. My brother does not share this match with us and it actually includes two sets of surnames and two single surnames with just one that has a tree (but just because they match this singleton match does not mean that they match my brother necessarily). This is actually his first match outside the family so is rather interesting. The tree shows a family with deep Virginia/North Carolina roots and then moving west from there as far as Texas. He is said to be a 4th-distant cousin. To look at X matches for a male the restriction is always towards the female, so our mother and her paternal grandmother and her mother/maternal grandparents but excluding the male line further back each time so always following the female portion plus the husband of the female at each level. That means I am looking at Grace Gray whose family lines were from Bewcastle, Cumberland and Etton/Holme on the Wolds East Riding of Yorkshire; I am looking at Ellen Rosina Buller whose father was born in Birmingham and his mother born at Lichfield with the father from Rugeley Staffordshire and the mother from Ashby de la Zouch Leicestershire and Ellen's mother who is my mystery lady born at Birmingham of parents possibly Thomas Taylor and Ellen Roberts whose lineage both stretches back one more generation at Birmingham and then unknown for Taylor and Warwickshire/Shropshire for the Roberts lines moving back. So a fifth cousin I am looking at 4x great grandparents and comparing that with a chart of ancestry that dates back into early colonial Virginia without any known debarkation point for the emigrant ancestor is virtually impossible. But it is interesting none the less to see that there is only one individual who matches my brother other than his sisters on the X chromosome. That tells me that not very many have tested in these lines but the potential is now there for them to do so as Ancestry moves into the British Isles.
One of my strongest X matches (3rd to 5th cousin with 60.32 cM shared) other than my siblings is with someone whose father's paternal grandmother came directly from Ireland born circa 1850. Anna Foster born 1850 Ireland and the daughter of Robert Foster. She is rather interesting because Anna would have received from her father Robert his only X chromosome passed directly to him from his mother and unaltered in this exchange. Anna then would have passed to her daughter in this case this X chromosome from her father and the one she received from her mother and the two would recombine to form a new X chromosome along with the X chromosome which she received from her father who again received it as passed from his mother whose family tree goes back into Yorkshire and Ireland (an interesting combination). Her mother's side is principally from Ohio/Missouri and before that Virginia. American ancestry is quite fascinating with the variety of ancestral locations to be found in their lines. Comparing her to other known lines she shares almost the same on the X chromosome as another match said to be 2nd to 4th cousin. On Chromosome 11 I have three people with known Irish ancestry who share DNA at almost the same location. Makes you wonder if this is a special block inherited by a number of Irish families. But the largest parts that I share with each of these four individuals including the one I am discussing are on different chromosomes. I need to have more people test that are known to me but that is really difficult given that we have no first cousins, few second cousins and half second cousins but many many third cousins that I do not personally know.
I shall continue working on the phasing of the X chromosomes with somewhat more knowledge than before I think. Discussion even with oneself can be quite beneficial if properly channelled! My living memory has been most beneficial to me and on occasion from comments received has proven to be handy to others which was a side product that I never anticipated when I started my blog in 2008.
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